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Thrombo-Inflammation in Cardiovascular Disease : An Expert Consensus Document from the Third Maastricht Consensus Conference on Thrombosis

d'Alessandro, Elisa (author)
Maastricht Univ, Med Ctr, Dept Biochem & Internal Med, Lab Clin Thrombosis & Hemostasis, Maastricht, Netherlands.;Maastricht Univ, Med Ctr, Thrombosis Expert Ctr, Maastricht, Netherlands.;CARIM Sch Cardiovasc Dis, Maastricht, Netherlands.
Becker, Christian (author)
Johannes Gutenberg Univ Mainz, Univ Med Ctr, Dept Dermatol, Mainz, Germany.
Bergmeier, Wolfgang (author)
Univ N Carolina, Dept Biochem & Biophys, McAllister Heart Inst, Chapel Hill, NC 27515 USA.
show more...
Bode, Christoph (author)
Univ Freiburg, Univ Heart Ctr Freiburg, Dept Cardiol & Angiol 1, Med Ctr, Bad Krozingen, Germany.
Bourne, Joshua H. (author)
Univ Birmingham, Coll Med & Dent Sci, Inst Cardiovasc Sci, Birmingham, W Midlands, England.
Brown, Helena (author)
DFG Forschungszentrum Expt Biomed, Rudolf Virchov Zentrum, Wurzburg, Germany.
Buller, Harry R. (author)
Univ Amsterdam, Med Ctr, Dept Vasc Med, Amsterdam, Netherlands.
ten Cate-Hoek, Arina J. (author)
Maastricht Univ, Med Ctr, Dept Biochem & Internal Med, Lab Clin Thrombosis & Hemostasis, Maastricht, Netherlands.;Maastricht Univ, Med Ctr, Thrombosis Expert Ctr, Maastricht, Netherlands.;CARIM Sch Cardiovasc Dis, Maastricht, Netherlands.;Stanford Univ, Sch Med, Div Hematol, Palo Alto, CA 94304 USA.;Palo Alto Vet Adm Hlth Care Syst, Palo Alto, CA USA.
ten Cate, Vincent (author)
Johannes Gutenberg Univ Mainz, Univ Med Ctr, Ctr Thrombosis & Hemostasis, Clin Epidemiol & Syst Med, Mainz, Germany.
van Cauteren, Yvonne J. M. (author)
CARIM Sch Cardiovasc Dis, Maastricht, Netherlands.;Maastricht Univ, Med Ctr, Dept Cardiol, Maastricht, Netherlands.
Cheung, Yam F. H. (author)
Leibniz Inst Analyt Wissensch ISAS, Dortmund, Germany.
Cleuren, Audrey (author)
Univ Michigan, Life Sci Inst, Ann Arbor, MI 48109 USA.
Coenen, Danielle (author)
CARIM Sch Cardiovasc Dis, Maastricht, Netherlands.;Maastricht Univ, Dept Biochem, Maastricht, Netherlands.
Crijns, Harry J. G. M. (author)
CARIM Sch Cardiovasc Dis, Maastricht, Netherlands.;Maastricht Univ, Med Ctr, Dept Cardiol, Maastricht, Netherlands.
de Simone, Ilaria (author)
CARIM Sch Cardiovasc Dis, Maastricht, Netherlands.;Maastricht Univ, Dept Biochem, Maastricht, Netherlands.
Dolleman, Sophie C. (author)
Leiden Univ, Med Ctr, Dept Internal Med Nephrol, Leiden, Netherlands.;Leiden Univ, Med Ctr, Einthoven Lab Expt Vasc & Regenerat Med, Leiden, Netherlands.
Klein, Christine Espinola (author)
Johannes Gutenberg Univ Mainz, Univ Med Ctr, Ctr Cardiol Cardiol 1, Mainz, Germany.
Fernandez, Delia I. (author)
CARIM Sch Cardiovasc Dis, Maastricht, Netherlands.;Maastricht Univ, Dept Biochem, Maastricht, Netherlands.
Granneman, Lianne (author)
Univ Med Ctr Utrecht, Dept Clin Chem & Haematol, Utrecht, Netherlands.
van t Hof, Arnoud (author)
CARIM Sch Cardiovasc Dis, Maastricht, Netherlands.;Maastricht Univ, Med Ctr, Dept Cardiol, Maastricht, Netherlands.;Stanford Univ, Sch Med, Div Hematol, Palo Alto, CA 94304 USA.;Palo Alto Vet Adm Hlth Care Syst, Palo Alto, CA USA.
Henke, Peter (author)
Michigan Med Vasc Surg Clin, Ctr Cardiovasc, Ann Arbor, MI USA.
Henskens, Yvonne M. C. (author)
CARIM Sch Cardiovasc Dis, Maastricht, Netherlands.;Maastricht Univ, Med Ctr, Cent Diagnost Lab, Maastricht, Netherlands.
Huang, Jingnan (author)
CARIM Sch Cardiovasc Dis, Maastricht, Netherlands.;Maastricht Univ, Dept Biochem, Maastricht, Netherlands.
Jennings, Lisa K. (author)
CirQuest Labs LLC, Memphis, TN USA.;Univ Tennessee, Ctr Hlth Sci, Memphis, TN 38163 USA.
Jooss, Natalie (author)
CARIM Sch Cardiovasc Dis, Maastricht, Netherlands.;Maastricht Univ, Dept Biochem, Maastricht, Netherlands.
Karel, Mieke (author)
CARIM Sch Cardiovasc Dis, Maastricht, Netherlands.;Maastricht Univ, Dept Biochem, Maastricht, Netherlands.
van den Kerkhof, Danique (author)
CARIM Sch Cardiovasc Dis, Maastricht, Netherlands.;Maastricht Univ, Dept Biochem, Maastricht, Netherlands.
Klok, Frederik A. (author)
Leiden Univ, Med Ctr, Dept Thrombosis & Hemostasis, Leiden, Netherlands.
Kremers, Bram (author)
Maastricht Univ, Med Ctr, Dept Biochem & Internal Med, Lab Clin Thrombosis & Hemostasis, Maastricht, Netherlands.;Maastricht Univ, Med Ctr, Thrombosis Expert Ctr, Maastricht, Netherlands.;CARIM Sch Cardiovasc Dis, Maastricht, Netherlands.
Laemmle, Bernhard (author)
Univ Bern, Bern Univ Hosp, Dept Hematol, Inselspital, Bern, Switzerland.;Univ Bern, Bern Univ Hosp, Cent Hematol Lab, Inselspital, Bern, Switzerland.;Johannes Gutenberg Univ Mainz, Univ Med Ctr, Ctr Thrombosis & Hemostasis, Mainz, Germany.;UCL, Haemostasis Res Unit, London, England.
Leader, Avi (author)
Maastricht Univ, Med Ctr, Dept Biochem & Internal Med, Lab Clin Thrombosis & Hemostasis, Maastricht, Netherlands.;Maastricht Univ, Med Ctr, Thrombosis Expert Ctr, Maastricht, Netherlands.;CARIM Sch Cardiovasc Dis, Maastricht, Netherlands.;Rabin Med Ctr, Dept Hematol, Petah Tiqwa, Israel.
Lundstrom, Annika (author)
Karolinska Institutet
Mackman, Nigel (author)
Univ N Carolina, UNC McAllister Heart Inst, Dept Med, Chapel Hill, NC 27515 USA.
Mannucci, Pier M. (author)
IRCCS Ca Granda Maggiore Policlin Hosp Fdn, Sci Direct, Milan, Italy.
Maqsood, Zahra (author)
DFG Forschungszentrum Expt Biomed, Rudolf Virchov Zentrum, Wurzburg, Germany.
van der Meijden, Paola E. J. (author)
Maastricht Univ, Med Ctr, Dept Biochem & Internal Med, Lab Clin Thrombosis & Hemostasis, Maastricht, Netherlands.;Maastricht Univ, Med Ctr, Thrombosis Expert Ctr, Maastricht, Netherlands.;CARIM Sch Cardiovasc Dis, Maastricht, Netherlands.;Maastricht Univ, Dept Biochem, Maastricht, Netherlands.
van Moorsel, Marc (author)
Univ Med Ctr Utrecht, Dept Clin Chem & Haematol, Utrecht, Netherlands.
Moran, Luis A. (author)
Univ Santiago de Compostela, CIMUS, Santiago De Compostela, Spain.
Morser, John (author)
Stanford Univ, Sch Med, Div Hematol, Palo Alto, CA 94304 USA.;Palo Alto Vet Adm Hlth Care Syst, Palo Alto, CA USA.
van Mourik, Manouk (author)
CARIM Sch Cardiovasc Dis, Maastricht, Netherlands.;Maastricht Univ, Med Ctr, Dept Cardiol, Maastricht, Netherlands.
Navarro, Stefano (author)
DFG Forschungszentrum Expt Biomed, Rudolf Virchov Zentrum, Wurzburg, Germany.
Neagoe, Raluca A. I. (author)
Univ Birmingham, Coll Med & Dent Sci, Inst Cardiovasc Sci, Birmingham, W Midlands, England.
Olie, Renske H. (author)
Maastricht Univ, Med Ctr, Dept Biochem & Internal Med, Lab Clin Thrombosis & Hemostasis, Maastricht, Netherlands.;Maastricht Univ, Med Ctr, Thrombosis Expert Ctr, Maastricht, Netherlands.;CARIM Sch Cardiovasc Dis, Maastricht, Netherlands.
van Paridon, Pauline (author)
Maastricht Univ, Med Ctr, Dept Biochem & Internal Med, Lab Clin Thrombosis & Hemostasis, Maastricht, Netherlands.;Maastricht Univ, Med Ctr, Thrombosis Expert Ctr, Maastricht, Netherlands.;CARIM Sch Cardiovasc Dis, Maastricht, Netherlands.
Posma, Jens (author)
Maastricht Univ, Med Ctr, Dept Biochem & Internal Med, Lab Clin Thrombosis & Hemostasis, Maastricht, Netherlands.;Maastricht Univ, Med Ctr, Thrombosis Expert Ctr, Maastricht, Netherlands.;CARIM Sch Cardiovasc Dis, Maastricht, Netherlands.
Provenzale, Isabella (author)
CARIM Sch Cardiovasc Dis, Maastricht, Netherlands.;Maastricht Univ, Dept Biochem, Maastricht, Netherlands.
Reitsma, Pieter H. (author)
Leiden Univ, Med Ctr, Dept Internal Med Nephrol, Leiden, Netherlands.;Leiden Univ, Med Ctr, Einthoven Lab Expt Vasc & Regenerat Med, Leiden, Netherlands.
Scaf, Billy (author)
Maastricht Univ, Med Ctr, Dept Biochem & Internal Med, Lab Clin Thrombosis & Hemostasis, Maastricht, Netherlands.;Maastricht Univ, Med Ctr, Thrombosis Expert Ctr, Maastricht, Netherlands.;CARIM Sch Cardiovasc Dis, Maastricht, Netherlands.
Schurgers, Leon (author)
CARIM Sch Cardiovasc Dis, Maastricht, Netherlands.;Maastricht Univ, Dept Biochem, Maastricht, Netherlands.
Seelig, Jaap (author)
Maastricht Univ, Med Ctr, Dept Biochem & Internal Med, Lab Clin Thrombosis & Hemostasis, Maastricht, Netherlands.;Maastricht Univ, Med Ctr, Thrombosis Expert Ctr, Maastricht, Netherlands.;CARIM Sch Cardiovasc Dis, Maastricht, Netherlands.;Rijnstate Ziekenhuis, Dept Cardiol, Arnhem, Netherlands.
Siegbahn, Agneta, 1947- (author)
Uppsala universitet,Klinisk kemi,Science for Life Laboratory, SciLifeLab,Stanford Univ, Sch Med, Div Hematol, Palo Alto, CA 94304 USA.;Palo Alto Vet Adm Hlth Care Syst, Palo Alto, CA USA
Siegerink, Bob (author)
Charite, Ctr Stroke Res Berlin, Berlin, Germany.
Soehnlein, Oliver (author)
Karolinska Institutet
Soriano, Eva Maria (author)
Univ Reading, Sch Biol Sci, Inst Cardiovasc & Metab Res, Reading, Berks, England.
Sowa, Marcin A. (author)
Univ Reading, Sch Biol Sci, Inst Cardiovasc & Metab Res, Reading, Berks, England.
Spronk, Henri M. H. (author)
Maastricht Univ, Med Ctr, Dept Biochem & Internal Med, Lab Clin Thrombosis & Hemostasis, Maastricht, Netherlands.;Maastricht Univ, Med Ctr, Thrombosis Expert Ctr, Maastricht, Netherlands.;CARIM Sch Cardiovasc Dis, Maastricht, Netherlands.
Storey, Robert F. (author)
Univ Sheffield, Dept Infect Immun & Cardiovasc Dis, Sheffield, S Yorkshire, England.
Tantiwong, Chukiat (author)
CARIM Sch Cardiovasc Dis, Maastricht, Netherlands.;Maastricht Univ, Dept Biochem, Maastricht, Netherlands.
Veninga, Alicia (author)
CARIM Sch Cardiovasc Dis, Maastricht, Netherlands.;Maastricht Univ, Dept Biochem, Maastricht, Netherlands.;Stanford Univ, Sch Med, Div Hematol, Palo Alto, CA 94304 USA.;Palo Alto Vet Adm Hlth Care Syst, Palo Alto, CA USA.
Wang, Xueqing (author)
Univ Birmingham, Coll Med & Dent Sci, Inst Cardiovasc Sci, Birmingham, W Midlands, England.
Watson, Steve P. (author)
Univ Birmingham, Coll Med & Dent Sci, Inst Cardiovasc Sci, Birmingham, W Midlands, England.
Weitz, Jeff (author)
Univ Sheffield, Dept Infect Immun & Cardiovasc Dis, Sheffield, S Yorkshire, England.;McMaster Univ, Dept Med, Div Hematol & Thromboembolism, Hamilton, ON, Canada.;McMaster Univ, Thrombosis & Atherosclerosis Res Inst, Hamilton, ON, Canada.
Zeerleder, Sacha S. (author)
Univ Bern, Bern Univ Hosp, Inselspital, Dept Haematol, Bern, Switzerland.;Univ Bern, Bern Univ Hosp, Inselspital, Cent Haematol Lab, Bern, Switzerland.;Univ Bern, Dept BioMed Res, Bern, Switzerland.
ten Cate, Hugo (author)
Maastricht Univ, Med Ctr, Dept Biochem & Internal Med, Lab Clin Thrombosis & Hemostasis, Maastricht, Netherlands.;Maastricht Univ, Med Ctr, Thrombosis Expert Ctr, Maastricht, Netherlands.;CARIM Sch Cardiovasc Dis, Maastricht, Netherlands.
Lina, Badimon (author)
Christoph, Binder (author)
Marc, Hoylaerts (author)
Peter, Karlheinz (author)
GregoryLip, Koenen Rory (author)
Steffen, Massberg (author)
Philipp, von Hundelshausen (author)
Christian, Weber (author)
Johann, Wojta (author)
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Maastricht Univ, Med Ctr, Dept Biochem & Internal Med, Lab Clin Thrombosis & Hemostasis, Maastricht, Netherlands;Maastricht Univ, Med Ctr, Thrombosis Expert Ctr, Maastricht, Netherlands.;CARIM Sch Cardiovasc Dis, Maastricht, Netherlands. Johannes Gutenberg Univ Mainz, Univ Med Ctr, Dept Dermatol, Mainz, Germany. (creator_code:org_t)
2020-04-14
2020
English.
In: Thrombosis and Haemostasis. - : Georg Thieme Verlag KG. - 0340-6245 .- 2567-689X. ; 120:4, s. 538-564
  • Journal article (peer-reviewed)
Abstract Subject headings
Close  
  • Thrombo-inflammation describes the complex interplay between blood coagulation and inflammation that plays a critical role in cardiovascular diseases. The third Maastricht Consensus Conference on Thrombosis assembled basic, translational, and clinical scientists to discuss the origin and potential consequences of thrombo-inflammation in the etiology, diagnostics, and management of patients with cardiovascular disease, including myocardial infarction, stroke, and peripheral artery disease. This article presents a state-of-the-art reflection of expert opinions and consensus recommendations regarding the following topics: (1) challenges of the endothelial cell barrier; (2) circulating cells and thrombo-inflammation, focused on platelets, neutrophils, and neutrophil extracellular traps; (3) procoagulant mechanisms; (4) arterial vascular changes in atherogenesis; attenuating atherosclerosis and ischemia/reperfusion injury; (5) management of patients with arterial vascular disease; and (6) pathogenesis of venous thrombosis and late consequences of venous thromboembolism.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Kardiologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)

Keyword

thrombosis
inflammation
coagulation
pulmonary embolism
myocardial infarction
stroke
platelets

Publication and Content Type

ref (subject category)
art (subject category)

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d'Alessandro, El ...
Becker, Christia ...
Bergmeier, Wolfg ...
Bode, Christoph
Bourne, Joshua H ...
Brown, Helena
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Buller, Harry R.
ten Cate-Hoek, A ...
ten Cate, Vincen ...
van Cauteren, Yv ...
Cheung, Yam F. H ...
Cleuren, Audrey
Coenen, Danielle
Crijns, Harry J. ...
de Simone, Ilari ...
Dolleman, Sophie ...
Klein, Christine ...
Fernandez, Delia ...
Granneman, Liann ...
van t Hof, Arnou ...
Henke, Peter
Henskens, Yvonne ...
Huang, Jingnan
Jennings, Lisa K ...
Jooss, Natalie
Karel, Mieke
van den Kerkhof, ...
Klok, Frederik A ...
Kremers, Bram
Laemmle, Bernhar ...
Leader, Avi
Lundstrom, Annik ...
Mackman, Nigel
Mannucci, Pier M ...
Maqsood, Zahra
van der Meijden, ...
van Moorsel, Mar ...
Moran, Luis A.
Morser, John
van Mourik, Mano ...
Navarro, Stefano
Neagoe, Raluca A ...
Olie, Renske H.
van Paridon, Pau ...
Posma, Jens
Provenzale, Isab ...
Reitsma, Pieter ...
Scaf, Billy
Schurgers, Leon
Seelig, Jaap
Siegbahn, Agneta ...
Siegerink, Bob
Soehnlein, Olive ...
Soriano, Eva Mar ...
Sowa, Marcin A.
Spronk, Henri M. ...
Storey, Robert F ...
Tantiwong, Chuki ...
Veninga, Alicia
Wang, Xueqing
Watson, Steve P.
Weitz, Jeff
Zeerleder, Sacha ...
ten Cate, Hugo
Lina, Badimon
Christoph, Binde ...
Marc, Hoylaerts
Peter, Karlheinz
GregoryLip, Koen ...
Steffen, Massber ...
Philipp, von Hun ...
Christian, Weber
Johann, Wojta
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Karolinska Institutet

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